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A novel EHD1/CD44/Hippo/SP1 positive feedback loop potentiates stemness and metastasis in lung adenocarcinoma
Clinical and Translational Medicine ( IF 7.919 ) Pub Date : 2022-04-29 , DOI: 10.1002/ctm2.836
Yuechao Liu 1 , Yang Song 2 , Mengru Cao 1 , Weina Fan 1 , Yaowen Cui 1 , Yimeng Cui 1 , Yuning Zhan 1 , Ruixue Gu 1 , Fanglin Tian 1 , Shuai Zhang 1 , Li Cai 1 , Ying Xing 1
Affiliation  

There is growing evidence that endocytosis plays a pivotal role in cancer metastasis. In this study, we first identified endocytic and metastasis-associated genes (EMGs) and then investigated the biological functions and mechanisms of EMGs.

中文翻译:

一种新的 EHD1/CD44/Hippo/SP1 正反馈环增强肺腺癌的干性和转移

越来越多的证据表明内吞作用在癌症转移中起关键作用。在这项研究中,我们首先确定了内吞和转移相关基因 (EMG),然后研究了 EMG 的生物学功能和机制。
更新日期:2022-04-29
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