A novel near-infrared fluorescent probe for the detection of sulfur dioxide derivatives and its application in biological imaging,New Journal of Chemistry

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A novel near-infrared fluorescent probe for the detection of sulfur dioxide derivatives and its application in biological imaging
New Journal of Chemistry ( IF 2.7 ) Pub Date : 2022-05-05 , DOI: 10.1039/d2nj01414a
Wanheng Wei ₁ , Wenjie Liu ₁ , Hongyan Zhang ₂ , Zhanxian Li ₁ , Mingming Yu ₁

Affiliation

SO₂ plays an important role in our life and is also associated with many diseases, so it is a double-edged sword. Therefore, it is necessary to develop a probe for detecting sulfur dioxide derivatives. Herein, on account of the Michael addition reaction mechanism, a near-infrared (NIR) fluorescent probe, HBQI, toward sulfur dioxide derivatives was developed, and the probe has high selectivity and strong anti-interference ability. The application study indicates that probe HBQI can detect sulfur dioxide derivatives in real water samples with good recovery. In addition, HBQI has been applied to live-cell imaging through confocal fluorescence techniques.

中文翻译：

一种新型近红外荧光探针检测二氧化硫衍生物及其在生物成像中的应用

SO ₂在我们的生活中扮演着重要的角色，也与很多疾病有关，所以它是一把双刃剑。因此，有必要开发一种检测二氧化硫衍生物的探针。在此，基于迈克尔加成反应机理，开发了一种针对二氧化硫衍生物的近红外（NIR）荧光探针HBQI，该探针具有高选择性和强抗干扰能力。应用研究表明，HBQI探头可以检测真实水样中的二氧化硫衍生物，具有良好的回收率。此外，HBQI 已通过共聚焦荧光技术应用于活细胞成像。

更新日期：2022-05-05

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