Metal-Free Synthesis of 1,3-Dioxane Derivatives from Aromatic Alkynes and Paraformaldehyde,Synlett

当前位置： X-MOL 学术 › Synlett › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Metal-Free Synthesis of 1,3-Dioxane Derivatives from Aromatic Alkynes and Paraformaldehyde
Synlett ( IF 1.7 ) Pub Date : 2022-04-12 , DOI: 10.1055/a-1823-1821
Xin Hu ₁ , Man Hua Ding ₁ , Fei Zeng ₁

Affiliation

Here we report the efficient synthesis of a series of 1,3-dioxane derivatives from aromatic alkynes, paraformaldehyde, and a Lewis acid catalyzed reaction at room temperature. This reaction is metal-free and atom-economic. Single crystals of two typical 1,3-dioxane derivatives are obtained. A mechanism that the reaction proceeds through a six- or eight-membered ring intermediate is proposed.

中文翻译：