Photocatalysis utilized solar energy with metal oxide semiconductors has been considered as one of the attractive green routes for organics’ conversion. The construction of high-density co-catalytic sites is essential for the surface reaction kinetics. In this work, a high-efficiency mesoporous TiO₂ decorated with single atomic Pt loading of 1 at% (2.1 wt%) had been successfully achieved. The high specific surface area of mesoporous TiO₂ affords adequate physical surface for the resident of atomic Pt, thus stabilizing a high areal density of single-atom reaction sites. The optimized single-atom Pt/TiO₂ revealed a performance of 4.1 mmol/h/g_cat for photocatalytic oxidation of benzyl alcohol under visible light irradiation that is 3.8 folds than that of Pt-modified commercial TiO₂ photocatalysts. The reactivity will further enhance after the introduction of plasmonic Au nanoparticles and the finally sample (1 at% Pt-0.075 at% Au)/TiO₂-MP exhibited salient activity (4.5 mmol/h/g_cat) and stability. This work paves a potential way to boost the performance of metal oxide semiconductors for green photocatalytic conversion of organics.