A two-stage, three-step synthesis of (R)-1-hydroxy-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid from 7-methoxy tetralone is described which employed an optimised Wittig olefination of 7-methoxytetralone and Sharpless asymmetric dihydroxylation followed by platinum-catalysed oxidation.

中文翻译：

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(R)-1-Hydroxy-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxy 酸的对映选择性合成的快速发展

描述了从 7-甲氧基四氢萘酮两步三步合成 (R)-1-羟基-7-甲氧基-1,2,3,4-四氢萘-1-羧酸的方法，该方法采用了优化的 Wittig 烯化7-甲氧基四氢萘酮和 Sharpless 不对称二羟基化，然后是铂催化氧化。