The salt formed from 2-chloro-4,6-dimethoxy[1,3,5]triazine and N-methylmorpholine (DMTMM) is an effective coupling agent for solid phase peptide synthesis that can be used as economical alternative to PyBOP. Several oligopeptides were prepared on a Wang type resin using this reagent and the yields and purity of the products were always comparable with those obtained with PyBOP as the coupling agent.

中文翻译：

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4-(4,6-Dimethoxy[1,3,5]triazin-2-yl)-4-methyl-morpholinium Chloride (DMTMM)：PyBOP 固相肽合成的有价值替代品

由 2-氯-4,6-二甲氧基[1,3,5]三嗪和 N-甲基吗啉 (DMTMM) 形成的盐是用于固相肽合成的有效偶联剂，可用作 PyBOP 的经济替代品。使用该试剂在 Wang 型树脂上制备了几种寡肽，产品的产率和纯度始终与使用 PyBOP 作为偶联剂获得的产品相当。