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Comparative analysis of chemical constituents in Citri Exocarpium Rubrum, Citri Reticulatae Endocarpium Alba, and Citri Fructus Retinervus
Food Science & Nutrition ( IF 3.5 ) Pub Date : 2022-04-22 , DOI: 10.1002/fsn3.2897
Wanling Yang 1 , Mengshi Liu 1 , Baizhong Chen 2 , Jinrong Ning 1 , Kanghui Wang 1 , Yi Cai 1 , Depo Yang 3 , Guodong Zheng 1
Affiliation  

Citri Exocarpium Rubrum (CER), Citri Reticulatae Endocarpium Alba (CREA), and Citri Fructus Retinervus (CFR) are used as medicine and food, which derive from three different parts of the pericarp of Citrus reticulata Blanco through natural drying. To systematically investigate similarities and differences in phytochemicals about the three herbs, a series of analytic approaches were applied for the qualitative and quantitative analysis of chemical constituents in them. The results indicated a total of 48 volatile compounds were determined representing 99.92% of the total relative content of CER extracts, including 24 alkenes, 11 alcohols, 6 aldehydes, 2 ketones, and 2 phenols, while volatile compounds were not extracted from CREA and CFR. CER was abundant in volatile components that mainly existed in the oil gland. And a total of 32, 35, and 28 nonvolatile compounds were identified from CER, CREA, and CFR extracts, respectively. The total content of flavonoids and phenolic, and hesperidin in CFR was the highest, followed by CREA and CER. Conversely, CER was a rich source of polymethoxyflavones (PMFs), and the total polymethoxyflavone content (TPMFC), the content of nobiletin, 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF), tangeretin, and 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone (5-HPMF) in CREA and CFR were extremely low. Besides, CER and CREA had a higher concentration of synephrine than CFR. The phytochemicals of CER, CREA, and CFR were significantly different, which might provide chemical evidence for the comparative pharmacological activities’ research and rational application of them.

中文翻译:


陈皮红、陈皮内皮、陈皮化学成分比较分析



Citri Exocarpium rubrum (CER)、Citri Reticulatae Endocarpium Alba (CREA) 和 Citri Fructus Retinervus (CFR) 用作药用和食品,由Citrus reticulata Blanco 果皮的三个不同部分经自然干燥而得。为了系统地研究这三种草药植物化学成分的异同,采用了一系列分析方法对它们的化学成分进行定性和定量分析。结果表明,共检出48种挥发性化合物,占CER提取物总相对含量的99.92%,其中烯烃24种,醇11种,醛6种,酮2种,酚2种,而CREA和CFR中未提取出挥发性化合物。 。 CER含有丰富的挥发性成分,主要存在于油腺中。从 CER、CREA 和 CFR 提取物中分别鉴定出总共 32、35 和 28 种非挥发性化合物。 CFR中黄酮类和酚类的总含量、橙皮苷含量最高,其次是CREA和CER。相反,CER是多甲氧基黄酮(PMF)的丰富来源,总多甲氧基黄酮含量(TPMFC)、川陈皮素、3,5,6,7,8,3',4'-七甲氧基黄酮(HMF)、橘皮素、 CREA 和 CFR 中的 5-羟基-6,7,8,3',4'-五甲氧基黄酮 (5-HPMF) 极低。此外,CER和CREA的辛弗林浓度高于CFR。 CER、CREA、CFR的植物化学成分存在显着差异,可为药理活性比较研究及合理应用提供化学依据。
更新日期:2022-04-22
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