New reactions of 3,4-dihydro-6,7-dimethoxyisoquinoline ylide with nitrile derivatives,Journal of Heterocyclic Chemistry

当前位置： X-MOL 学术 › J. Heterocycl. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

New reactions of 3,4-dihydro-6,7-dimethoxyisoquinoline ylide with nitrile derivatives
Journal of Heterocyclic Chemistry ( IF 2.0 ) Pub Date : 2022-04-20 , DOI: 10.1002/jhet.4496
Márk Molnár ₁ , Krisztina E. Treuerne Balázs ₂ , Zoltán Madarász ₁ , Miklós Nyerges ₁

Affiliation

Novel examples for dipolar cycloaddition of isoquinolinium ylides to nitriles leading to new imidazo[2,1-a]isoquinolines were described and the potential of this reaction in synthetic chemistry was explored. As a by-product of this research, a number of N-substituted, 3,4-dihydro-1H-isoquinoline-1-carbonitriles were synthesized by a simple, efficient reaction of a series of isoquinolinium bromides and ethyl cyanoformate in the presence of triethylamine.

中文翻译：

3,4-二氢-6,7-二甲氧基异喹啉叶立德与腈衍生物的新反应

描述了异喹啉叶立德与腈的偶极环加成产生新的咪唑并[2,1- a ]异喹啉的新例子，并探索了该反应在合成化学中的潜力。作为本研究的副产品，通过一系列异喹啉溴化物和氰基甲酸乙酯在存在下进行简单、高效的反应，合成了许多N-取代的 3,4-二氢-1 H-异喹啉-1-甲腈。三乙胺。

更新日期：2022-04-20

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南