A novel 2-bromo-5-(2-(methylthio)phenyl)thiophene compound generated selective cytotoxicity on LnCap, Caco-2 and HepG2 lines but not on the control cell line HEK293. This derivative is proposed to have regulatory and/or rousing outcomes in apoptosis signaling pathways via changes in caspase3, Bcl-2 and Bax expressions related with GSH pool and GST activities. It has antibacterial activity against S.aureus, too.

中文翻译：

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噻吩衍生物 2-Bromo-5-(2-(甲硫基)苯基)噻吩具有有效的抗癌潜力和其他生物学特性

一种新型 2-溴-5-(2-(甲硫基)苯基)噻吩化合物对 LnCap、Caco-2 和 HepG2 系产生选择性细胞毒性，但对对照细胞系 HEK293 没有。该衍生物被提议通过与 GSH 池和 GST 活性相关的 caspase3、Bcl-2 和 Bax 表达的变化在细胞凋亡信号通路中产生调节和/或唤醒结果。它对金黄色葡萄球菌也有抗菌活性。