A near-infrared probe for detecting and interposing amyloid beta oligomerization in early Alzheimer's disease,Alzheimer's & Dementia

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A near-infrared probe for detecting and interposing amyloid beta oligomerization in early Alzheimer's disease
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2022-04-18 , DOI: 10.1002/alz.12673
Li Quan _{1,

2} , Ines Moreno-Gonzalez _{3,

4,

5} , Zhigang Xie ₆ , Nazaret Gamez _{3,

4} , Laura Vegas-Gomez ₄ , Qinyong Song ₁ , Jianhua Gu ₇ , Wenhai Lin ₆ , Ruben Gomez-Gutierrez _{3,

4} , Tianfu Wu ₂

Affiliation

The misfolding and deposition of amyloid beta (Aβ) in human brain is the main hallmark of Alzheimer's disease (AD) pathology. One of the drivers of Alzheimer´s pathogenesis is the production of soluble oligomeric Aβ, which could potentially serve as a biomarker of AD.

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