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Development of an Electrodeposited Graphene Quantum Dot Electrode for the Electrochemical Detection of C-Reactive Protein (CRP) Biomarker
ChemistrySelect ( IF 1.9 ) Pub Date : 2022-04-07 , DOI: 10.1002/slct.202104511 Muthaiyan Lakshmanakumar 1, 2 , Noel Nesakumar 3 , Swaminathan Sethuraman 2, 3 , K. S. Rajan 2, 3 , Uma Maheswari Krishnan 2, 3, 4 , John Bosco Balaguru Rayappan 1, 2
ChemistrySelect ( IF 1.9 ) Pub Date : 2022-04-07 , DOI: 10.1002/slct.202104511 Muthaiyan Lakshmanakumar 1, 2 , Noel Nesakumar 3 , Swaminathan Sethuraman 2, 3 , K. S. Rajan 2, 3 , Uma Maheswari Krishnan 2, 3, 4 , John Bosco Balaguru Rayappan 1, 2
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A facile method to synthesize graphene quantum dots (GQDs) with a diameter of 2.2 nm. GQDs were electrodeposited successfully on the surface of the Au electrode to fabricate the Au/GQDs/anti-CRP electrode. The figure of merits of the developed sensor with a high sensitivity of 58 μA ng−1 mL−1 cm−2 and a low detection capability of 0.104 ng mL−1. And also the fabricated Au/GQDs/anti-CRP biosensor was used to detect CRP (C-Reactive Protein) concentrations in a ringer lactate (artificial serum) solution.
中文翻译：
用于电化学检测 C 反应蛋白 (CRP) 生物标志物的电沉积石墨烯量子点电极的开发
一种合成直径为 2.2 nm 的石墨烯量子点 (GQD) 的简便方法。将GQDs成功电沉积在Au电极表面，制备了Au/GQDs/anti-CRP电极。所开发传感器的品质因数具有58 μA ng -1 mL -1 cm -2的高灵敏度和0.104 ng mL -1的低检测能力。并且还使用制造的 Au/GQDs/抗 CRP 生物传感器来检测林格乳酸（人工血清）溶液中的 CRP（C 反应蛋白）浓度。
更新日期：2022-04-07
中文翻译：
用于电化学检测 C 反应蛋白 (CRP) 生物标志物的电沉积石墨烯量子点电极的开发
一种合成直径为 2.2 nm 的石墨烯量子点 (GQD) 的简便方法。将GQDs成功电沉积在Au电极表面，制备了Au/GQDs/anti-CRP电极。所开发传感器的品质因数具有58 μA ng -1 mL -1 cm -2的高灵敏度和0.104 ng mL -1的低检测能力。并且还使用制造的 Au/GQDs/抗 CRP 生物传感器来检测林格乳酸（人工血清）溶液中的 CRP（C 反应蛋白）浓度。
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