当前位置：
X-MOL 学术
›
Proc. Natl. Acad. Sci. U.S.A.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
JAK抑制剂的网络药理学[免疫学和炎症]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2016-08-30 09:27:57 , DOI: 10.1073/pnas.1610253113
Devapregasan Moodley 1 , Hideyuki Yoshida 1 , Sara Mostafavi 2, 3 , Natasha Asinovski 1 , Adriana Ortiz-Lopez 1 , Peter Symanowicz 4 , Jean-Baptiste Telliez 4 , Martin Hegen 4 , James D. Clark 4 , Diane Mathis 1 , Christophe Benoist 1
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2016-08-30 09:27:57 , DOI: 10.1073/pnas.1610253113
Devapregasan Moodley 1 , Hideyuki Yoshida 1 , Sara Mostafavi 2, 3 , Natasha Asinovski 1 , Adriana Ortiz-Lopez 1 , Peter Symanowicz 4 , Jean-Baptiste Telliez 4 , Martin Hegen 4 , James D. Clark 4 , Diane Mathis 1 , Christophe Benoist 1
Affiliation
|
尽管增加某些感染的风险，但Janus激酶家族（JAKis）的小分子抑制剂在多种自身免疫性疾病中具有临床疗效。它们的确切作用机理尚不清楚，JAK是多种细胞因子的信号枢纽。我们评估了泛和异构体特异性JAKi对小鼠的体内影响...
"点击查看英文标题和摘要"
更新日期：2016-09-01
"点击查看英文标题和摘要"
京公网安备 11010802027423号