Cataluminescence sensor was useful for rapid determination of acetone in exhaled breath, which was a biomarker of diabetes. In Pt NPs@NU-901 nanocomposite, Pt NPs were dispersed in the elliptical structure of NU-901 successfully, and the original structure of NU-901 was kept intact. The CTL signal of acetone indicated that Pt NPs@NU-901 has the best catalytic performance. The introduction of Pt NPs improves the catalytic performance of nanocomposites effectively, and the coordination with acetone increased the adsorption energy by more than 8 times. Pt NPs@NU-901 integrated rapid capture, catalysis with detection of acetone, then the CTL method based on Pt NPs@NU-901 was established for rapid determination of acetone content in exhaled breath, the linear range was 0.50–70.0 mg/L, limit of detection was 0.23 mg/L (S/N = 3). RSDs for repeatability and reproducibility experiments were 4.8% and 4.5%, respectively. Acetone content in exhaled breath samples was detected by the method with recoveries from 90.6% to 107%. Notable, results of samples were consistent with that obtained from gas chromatography, indicating that the established CTL method was accurate, stable and rapid, and provided a guarantee for rapid and nondestructive screening of diabetic patients.

催化发光传感器可用于快速测定呼出气中的丙酮，丙酮是糖尿病的生物标志物。在 Pt NPs@NU-901 纳米复合材料中，Pt NPs 成功地分散在 NU-901 的椭圆结构中，并且保持了 NU-901 的原始结构。丙酮的CTL信号表明Pt NPs@NU-901的催化性能最好。Pt NPs的引入有效提高了纳米复合材料的催化性能，与丙酮的配位使吸附能提高了8倍以上。Pt NPs@NU-901集快速捕获、催化和丙酮检测于一体，建立了基于Pt NPs@NU-901的CTL法快速测定呼气中丙酮含量，线性范围为0.50~70.0 mg/L , 检出限为 0.23 mg/L ( S/N = 3)。重复性和再现性实验的 RSD 分别为 4.8% 和 4.5%。用该方法检测呼出气样品中的丙酮含量，回收率从 90.6% 到 107%。值得注意的是，样品结果与气相色谱结果一致，表明所建立的CTL方法准确、稳定、快速，为糖尿病患者的快速无损筛查提供了保障。