Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications,Journal of Agricultural and Food Chemistry

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Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2022-03-29 , DOI: 10.1021/acs.jafc.2c00010
Dan Liu _{1,

2} , Xiao-Qin He ₂ , Ding-Tao Wu ₁ , Hua-Bin Li ₃ , Yi-Bin Feng ₄ , Liang Zou ₁ , Ren-You Gan _{1,

2}

Affiliation

Elderberry (Sambucus nigra L.) is rich in many bioactive compounds and exhibits diverse health functions, of which an understanding can be helpful for its better utilization in the food industry. This review mainly summarizes recent studies about the bioactive compounds and health functions of elderberry, highlighting the potential mechanism of action. In addition, the applications of elderberry in foods are also discussed. Elderberry contains diversely bioactive ingredients, such as (poly)phenolic compounds and terpenoid compounds. Recent studies report that some food processing methods can affect the content of bioactive compounds in elderberry. Additionally, elderberry exhibits various health functions in vitro and in vivo, including antioxidant, anti-inflammatory, anticancer, anti-influenza, antimicrobial, antidiabetic, cardiovascular protective, and neuroprotective activities, and their potential molecular mechanisms are associated with regulating some key signaling pathways and molecular targets. Up to now, there have been limited clinical trials supporting the health benefits of elderberry. Overall, elderberry is a promising dietary source of bioactive ingredients and has the potential to be developed into functional foods or nutraceuticals for preventing and treating certain chronic diseases.

中文翻译：

接骨木 (Sambucus nigra L.)：生物活性化合物、健康功能和应用

接骨木莓（Sambucus nigra L.）富含多种生物活性化合物，具有多种保健功能，了解这些有助于更好地利用其在食品工业中的应用。这篇综述主要总结了最近关于接骨木的生物活性化合物和健康功能的研究，突出了潜在的作用机制。此外，还讨论了接骨木在食品中的应用。接骨木果含有多种生物活性成分，例如（多）酚类化合物和萜类化合物。最近的研究报告说，一些食品加工方法会影响接骨木中生物活性化合物的含量。此外，接骨木果在体外和体内表现出多种保健功能包括抗氧化、抗炎、抗癌、抗流感、抗菌、抗糖尿病、心血管保护和神经保护活性，其潜在的分子机制与调节一些关键信号通路和分子靶点有关。到目前为止，支持接骨木浆果的健康益处的临床试验有限。总体而言，接骨木果是一种很有前景的生物活性成分膳食来源，并有可能被开发成用于预防和治疗某些慢性疾病的功能性食品或营养保健品。

更新日期：2022-03-29

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