New potential of boron-based COFs: the biocompatible COF-1 for reactive oxygen generation and antimicrobial applications,Journal of Materials Chemistry B

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New potential of boron-based COFs: the biocompatible COF-1 for reactive oxygen generation and antimicrobial applications
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2022-03-23 , DOI: 10.1039/d1tb02808a
Yiying Zhang ₁ , Xiaoqing Xu ₂ , Qiaobo Liao ₁ , Qiaomu Wang ₁ , Qingwen Han ₁ , Pengpeng Chen ₂ , Kai Xi ₁

Affiliation

Photocatalytic covalent organic frameworks (COFs) are popular in the field of biomedical materials and also have potential as antimicrobial materials. Herein, a boron-based COF was used in antibacterial applications innovatively. The results of this study suggested that COF-1, the earliest boroxine COF, could produce a variety of reactive oxygen species (ROS) under visible light irradiation. In order to explore more applications of COF-1, antibacterial tests were carried out based on the above results. The test results showed that the material displayed an obvious bactericidal effect on Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by releasing ROS under white light. According to the results of plate coating, all bacteria died after co-cultivation with COF-1 under white light for about 120 minutes. In a word, this study could provide a new idea for the application of boron-based COFs as multifunctional photocatalysts in future.

中文翻译：

硼基 COF 的新潜力：用于活性氧生成和抗菌应用的生物相容性 COF-1

光催化共价有机框架（COFs）在生物医学材料领域很受欢迎，也具有作为抗菌材料的潜力。在此，一种基于硼的 COF 被创新地用于抗菌应用。这项研究的结果表明，最早的环硼氧化合物COF-1在可见光照射下可以产生多种活性氧(ROS)。为了探索COF-1的更多应用，基于上述结果进行了抗菌试验。试验结果表明，该材料对大肠杆菌（E.coli）和金黄色葡萄球菌（S.aureus ）具有明显的杀菌作用。) 通过在白光下释放 ROS。根据平板涂布结果，在白光下与COF-1共培养约120分钟后，所有细菌均死亡。总之，本研究可为未来硼基COFs作为多功能光催化剂的应用提供新思路。

更新日期：2022-03-23

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