Classification of adult-type diffuse gliomas: Impact of the World Health Organization 2021 update,Brain Pathology

当前位置： X-MOL 学术 › Brain Pathol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Classification of adult-type diffuse gliomas: Impact of the World Health Organization 2021 update
Brain Pathology ( IF 5.8 ) Pub Date : 2022-03-14 , DOI: 10.1111/bpa.13062
Benjamin T. Whitfield ₁ , Jason T. Huse ₁

Affiliation

Over the last decade, developments in molecular profiling have radically altered the diagnosis, classification, and management of numerous cancer types, with primary brain tumors being no exception. Although historically brain tumors have been classified based on their morphological characteristics, recent advances have allowed refinement of tumor classification based on molecular alterations. This shift toward molecular classification of primary brain tumors is reflected in the 2021 5^th edition of the WHO classification of central nervous system tumors (WHO 2021). In this review, we will discuss the most recent updates to the classification of adult-type diffuse gliomas, a group of highly infiltrative and largely incurable CNS malignancies. It is our hope continued that refinement of molecular criteria will improve diagnosis, prognostication, and eventually treatment of these devastating tumors.

中文翻译：

成人型弥漫性胶质瘤的分类：世界卫生组织 2021 年更新的影响

在过去十年中，分子分析的发展从根本上改变了多种癌症类型的诊断、分类和管理，原发性脑肿瘤也不例外。尽管历史上脑肿瘤是根据其形态特征进行分类的，但最近的进展已经允许基于分子改变对肿瘤分类进行细化。这种向原发性脑肿瘤分子分类的转变反映在 2021 年第 5^届世界卫生组织中枢神经系统肿瘤分类版（WHO 2021）。在这篇综述中，我们将讨论成人型弥漫性胶质瘤分类的最新更新，这是一组高度浸润性和基本上无法治愈的 CNS 恶性肿瘤。我们希望继续改进分子标准将改善这些破坏性肿瘤的诊断、预后和最终治疗。

更新日期：2022-03-14

点击分享查看原文

点击收藏

公开下载

阅读更多本刊新发论文本刊介绍/投稿指南