A series of thermodynamic parameters of N-hexylpyridinium bromide ([Hpy]Br) ionic liquid (IL) were investigated by inverse gas chromatography (IGC) technique. These parameters included the Flory-Huggins interaction parameters (${\chi }_{12}$), activity coefficients at infinite dilution (${\gamma }_{12}^{\infty }$), molar heat (enthalpy) of probe absorption in the [Hpy]Br ($\Delta H_1^S$), molar heat of mixing at infinite dilution between [Hpy]Br and probe ($\Delta H_1^{\infty }$), and Hildebrand solubility parameters (${\delta }_2$). The isothermal vapor-liquid equilibrium (VLE) data of [Hpy]Br and solvents with good solubility at 353.15K were determined from ${\chi }_{12}$ and correlated with the NRTL model. The potential of [Hpy]Br as an entrainer for separating benzene (1)/ethanol (2), benzene (1)/isopropanol (2), and benzene (1)/thiophene (2) azeotropic mixture by extractive distillation was explored using the y-$x^{\prime }$ diagram. Results showed that the azeotropy of three binary systems could be broken by adding [Hpy]Br and the reliability of thermodynamic analyses was verified.

采用反气相色谱（IGC）技术研究了N-己基溴化吡啶（[Hpy]Br）离子液体（IL）的一系列热力学参数。这些参数包括 Flory-Huggins 交互参数 (${\chi }_{12}$），无限稀释时的活度系数（${\gamma }_{12}^{\infty }$), [Hpy]Br ($\Delta H_1^{\mathrm{小号}}$), [Hpy]Br 和探针之间无限稀释时的摩尔混合热 ($\Delta H_1^{\infty }$) 和 Hildebrand 溶解度参数 (${\delta }_2$）。[Hpy]Br 和在 353.15K 下具有良好溶解度的溶剂的等温汽液平衡 (VLE) 数据由下式确定${\chi }_{12}$并与 NRTL 模型相关。[Hpy]Br 作为共沸剂通过萃取蒸馏分离苯 (1)/乙醇 (2)、苯 (1)/异丙醇 (2) 和苯 (1)/噻吩 (2) 共沸混合物的潜力y - _$X^{\text{'}}$图表。结果表明，加入[Hpy]Br可以打破三个二元体系的共沸现象，验证了热力学分析的可靠性。