Pyrazolo[3,4-d]pyrimidine as a bioisostere of purine has drawn considerable attention as a privileged scaffold for the design and discovery of novel drugs. Green synthesis is an emerging area in the field of chemistry that provides economic and environmental benefits as an alternative to traditional methods. The present mini review reflects recent advances in the green synthesis of pyrazolo[3,4-d]pyrimidines, published in the time frame from 2006 to 2019.

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吡唑并[3,4-d]嘧啶合成的最新绿色方法：小型综述

吡唑并[3,4- d ]嘧啶作为嘌呤的生物等排体，作为设计和发现新药的特殊支架引起了相当大的关注。绿色合成是化学领域的一个新兴领域，可作为传统方法的替代方案提供经济和环境效益。本小型综述反映了2006 年至 2019 年时间框架内出版的吡唑并[3,4- d ]嘧啶绿色合成的最新进展。