By virtue of diverse structures and tunable properties, MIL-88(Fe) and modified materials displayed extensive applications including biosensor, energy storage, catalytic oxidation and emulsion separation. In recent years, synthesis of MIL-88(Fe) and their derived nanomaterials provided an opportunity to obtain outstanding advanced oxidation performances due to their lightly accessible inner surface, controllable composition and pore structure. In addition, it was also demonstrated that the enhancement of advanced oxidation performance was associated with the combination of additional porous structures to increase the surface area and provide more active sites. In the meantime, a mechanism of MIL-88(Fe)-derived photocatalyst in catalytic reaction process are highlighted. The preparation methods of the materials and their respective advantages were also mentioned in the paper. Finally, a perspective for future development of MIL-88(Fe) and their derivatives as catalysts for advanced oxidation performances was discussed.