Biodegradable magnesium phosphates in biomedical applications,Journal of Materials Chemistry B

当前位置： X-MOL 学术 › J. Mater. Chem. B › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Biodegradable magnesium phosphates in biomedical applications
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2022-02-11 , DOI: 10.1039/d1tb02836g
Xiang Gu ₁ , Yan Li ₁ , Chao Qi ₁ , Kaiyong Cai ₁

Affiliation

As an essential element, magnesium is involved in a variety of physiological processes. Magnesium is the second most abundant cation in cells and the fourth most abundant cation in living organisms. Magnesium-based biomaterials are considered to be biocompatible and biodegradable, and they are promising for application in biomedicine. Among them, magnesium phosphates have attracted increasing interest in biomedical fields in recent years, because both magnesium and phosphorus are common elements in the human body. Magnesium phosphates exhibit many similar characteristics, such as excellent biocompatibility and pH-responsive degradability, to calcium phosphates that are widely applied in biomedicine. Magnesium phosphates are used in nanomedicine in the form of monodisperse particles, or used in tissue engineering in the form of cements, ceramics, scaffolds, coatings and so on. This review focuses on the state-of-the-art progress made in magnesium phosphate-based biomaterials and their biomedical applications, including nanostructured magnesium phosphates and magnesium phosphate-based cements, ceramics, scaffolds, coatings and so on. Finally, the challenges and future research directions of magnesium phosphate-based biomaterials are also explored.

中文翻译：

生物医学应用中的可生物降解磷酸镁

作为一种必需元素，镁参与多种生理过程。镁是细胞中第二丰富的阳离子，也是生物体中第四丰富的阳离子。镁基生物材料被认为具有生物相容性和可生物降解性，在生物医学中的应用前景广阔。其中，磷酸镁近年来在生物医学领域引起了越来越多的关注，因为镁和磷都是人体中常见的元素。磷酸镁与广泛应用于生物医学的磷酸钙具有许多相似的特性，例如优异的生物相容性和pH响应降解性。磷酸镁以单分散颗粒的形式用于纳米医学，或以水泥、陶瓷、支架、涂料等。本综述重点介绍了磷酸镁基生物材料及其生物医学应用的最新进展，包括纳米结构的磷酸镁和磷酸镁基水泥、陶瓷、支架、涂料等。最后，还探讨了磷酸镁基生物材料面临的挑战和未来的研究方向。

更新日期：2022-02-11

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南