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A smart probe for simultaneous imaging of the lipid/water microenvironment in atherosclerosis and fatty liver
Chemical Communications ( IF 4.3 ) Pub Date : 2022-02-23 , DOI: 10.1039/d2cc00795a Zixuan Zhan 1 , Weihua Zhuang 2 , Qian Lei 1 , Shufen Li 2 , Wuyu Mao 1 , Mao Chen 2 , Weimin Li 1
Chemical Communications ( IF 4.3 ) Pub Date : 2022-02-23 , DOI: 10.1039/d2cc00795a Zixuan Zhan 1 , Weihua Zhuang 2 , Qian Lei 1 , Shufen Li 2 , Wuyu Mao 1 , Mao Chen 2 , Weimin Li 1
Affiliation
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A smart lipid droplet specific fluorescent probe (LDs-DM) with dual-emission in water (706 nm) and oil (535 nm) under single-excitation was prepared for revealing the ultra-structure of the aqueous and lipidic microenvironment in living cells, fatty liver tissues and atherosclerotic plaques without fluorescence emission crosstalk. This work is expected to provide inspiration for designing a novel probe with color switching ability.
中文翻译：
用于同时成像动脉粥样硬化和脂肪肝中脂质/水微环境的智能探针
制备了单激发下水（706 nm）和油（535 nm）双发射的智能脂滴特异性荧光探针（LDs-DM ），用于揭示活细胞水和脂质微环境的超微结构，无荧光发射串扰的脂肪肝组织和动脉粥样硬化斑块。这项工作有望为设计具有颜色切换能力的新型探针提供灵感。
更新日期：2022-02-23
中文翻译：
用于同时成像动脉粥样硬化和脂肪肝中脂质/水微环境的智能探针
制备了单激发下水（706 nm）和油（535 nm）双发射的智能脂滴特异性荧光探针（LDs-DM ），用于揭示活细胞水和脂质微环境的超微结构，无荧光发射串扰的脂肪肝组织和动脉粥样硬化斑块。这项工作有望为设计具有颜色切换能力的新型探针提供灵感。
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