Novel poly(vinylidene fluoride) (PVDF) ultrafiltration membranes blending with chiral mesoporous SiO₂ materials were constructed to improve the anti-fouling and separation performance of PVDF-blended membranes. The formation of asymmetric mesoporous structure of chiral mesoporous SiO₂ caused their large hydrophilic surface and significant chiral features, which enhanced the hydrophilicity and polarity of the resulting PVDF membranes blended with chiral mesoporous SiO₂. So, the PVDF-blended membranes containing chiral mesoporous SiO₂ had a high permeation performance and anti-fouling property. After blending with chiral mesoporous SiO₂, the maximum flux of membranes exceeded 500 L·m⁻²·h⁻¹ and was 6.5-fold higher than that of neat PVDF. Due to the stereo-specific interaction between enantiomers and chiral recognition sites introduced by chiral mesoporous SiO₂ in the membranes, all PVDF-blended membranes had evident enantioseparation performance for DL-racemic tryptophan. The C-SiO₂-20/PVDF-blended membranes had the highest enantioseparation performance under the same addition content and the maximum enantiomeric excess (e.e.%) was more than 20 %. Given the strong stereo-specific interaction and hydrogen bonding between d-tryptophan and β-cyclodextrin (β-CD), the addition of more β-CD would introduce more chiral recognition sites into the membranes, thereby enhancing the enantioseparation performance of the membranes for d-tryptophan. The maximum e.e.% of C-SiO₂-20/β-CD/PVDF-blended membranes for the tryptophan enantiomer reached 55%.

_{构建了与手性介孔SiO 2}材料共混的新型聚偏氟乙烯（PVDF）超滤膜，以提高PVDF共混膜的防污和分离性能。_{手性介孔SiO 2}不对称介孔结构的形成使其具有较大的亲水表面和显着的手性特征，从而增强了与手性介孔SiO ₂共混的PVDF膜的亲水性和极性。_{因此，含有手性介孔SiO 2}的PVDF共混膜具有较高的渗透性能和防污性能。与手性介孔SiO ₂共混后，膜的最大通量超过500 L·m ^-2·h ^-1比纯 PVDF 高 6.5 倍。_{由于对映体和手性介孔SiO 2}在膜中引入的手性识别位点之间的立体特异性相互作用，所有PVDF共混膜对DL-外消旋色氨酸具有明显的对映分离性能。C-SiO ₂-20/PVDF共混膜在相同添加量下对映体分离性能最高，最大对映体过量（ee%）大于20%。鉴于 d-色氨酸和 β-环糊精 (β-CD) 之间的强立体特异性相互作用和氢键结合，添加更多的 β-CD 将在膜中引入更多的手性识别位点，从而提高膜的对映体分离性能d-色氨酸。色氨酸对映体的C-SiO ₂ -20/β-CD/PVDF共混膜的最大ee%达到55%。