Objectives Numerous natural products, including rhamnetin, have been studied in recent years owing to the need for new herbal remedies to treat different illnesses. This study aimed to review the salient properties of rhamnetin and its pharmacological potential and possible toxicological effects. Key findings A search carried out in the ScienceDirect database using the term ‘rhamnetin’ yielded 573 articles published between 1977 and 2021. However, only those studies that mentioned pharmacological activity of rhamnetin were included in this study. As a result of this selection process, this study included reports that describe rhamnetin as a secondary metabolite with several pharmacological properties. Summary Rhamnetin (2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one) is a secondary metabolite, belonging to the flavonoid class, present in various plants and fruits; it has different pharmacological properties, including antioxidant, anticancer, anti-inflammatory, antiviral and antibacterial activity. However, conclusive results on the toxicology of rhamnetin have not been reported yet. Therefore, further research is needed to gather detailed information about the effects of rhamnetin.

中文翻译：

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鼠李素：药理学和毒性综述

目的 由于需要新的草药来治疗不同的疾病，近年来已经研究了许多天然产品，包括鼠李素。本研究旨在回顾鼠李素的显着特性及其药理潜力和可能的毒理作用。主要发现 在 ScienceDirect 数据库中使用“鼠李素”一词进行的搜索产生了 1977 年至 2021 年间发表的 573 篇文章。然而，只有那些提到鼠李素药理活性的研究才被纳入本研究。由于这一选择过程，本研究包括将鼠李素描述为具有多种药理特性的次级代谢物的报告。总结 鼠李素 (2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one) 是一种次级代谢产物，属于黄酮类，存在于各种植物和水果中；它具有不同的药理特性，包括抗氧化、抗癌、抗炎、抗病毒和抗菌活性。然而，关于鼠李素毒理学的结论性结果尚未见报道。因此，需要进一步研究以收集有关鼠李素作用的详细信息。