Influence of extracorporeal cytokine adsorption on hemodynamics in severe acute pancreatitis: Results of the matched cohort pancreatitis cytosorbents inflammatory cytokine removal (PACIFIC) study,Artificial Organs

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Influence of extracorporeal cytokine adsorption on hemodynamics in severe acute pancreatitis: Results of the matched cohort pancreatitis cytosorbents inflammatory cytokine removal (PACIFIC) study
Artificial Organs ( IF 2.2 ) Pub Date : 2022-02-19 , DOI: 10.1111/aor.14195
Sebastian Rasch ₁ , Sengül Sancak ₁ , Johanna Erber ₁ , Johannes Wießner ₁ , Dominik Schulz ₁ , Christina Huberle ₁ , Hana Algül _{1,

2} , Roland M Schmid ₁ , Tobias Lahmer ₁

Affiliation

Outcome of severe acute pancreatitis (SAP) highly depends on the degree of systemic inflammation and organ failure. Although treatment approaches targeting the inflammatory cascade have failed in pancreatitis, recent studies suggest that extracorporeal cytokine adsorption effectively reduces concentrations of pro-inflammatory cytokines and potentially improves the outcome of sepsis.

中文翻译：

体外细胞因子吸附对重症急性胰腺炎血流动力学的影响：匹配队列胰腺炎细胞吸附剂炎性细胞因子去除 (PACIFIC) 研究的结果

重症急性胰腺炎 (SAP) 的结局很大程度上取决于全身炎症和器官衰竭的程度。尽管针对炎症级联反应的治疗方法在胰腺炎中失败了，但最近的研究表明，体外细胞因子吸附有效地降低了促炎细胞因子的浓度，并可能改善脓毒症的结果。

更新日期：2022-02-19

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