Abstract

In this study, two series of novel diacylhydrazine derivatives containing an isoxazole carboxamide or a pyridine carboxamide moiety have been synthesized and their structures confirmed by ¹H and ¹³C NMR, and mass spectra. According to bioassay data LC₅₀ values for the product 3-(2-chlorophenyl)-N-{2-[2-(2,6-difluorobenzoyl)hydrazinecarbonyl]-4-fluorophenyl}-5-methylisoxazole-4-carboxamide (5f) against Plutella xylostella (P. xylostella) and Empoasca vitis (E. vitis) have been determined to be 1.67 and 1.29 mg/L, respectively, that were higher than those of spinosad, chlorpyrifos, beta cypermethrin, and azadirachtin.

中文翻译：

---

含有异恶唑甲酰胺或吡啶甲酰胺部分的新型二酰基肼衍生物的设计、合成和杀虫活性

摘要

在本研究中，合成了两个含有异恶唑甲酰胺或吡啶甲酰胺部分的新型二酰基肼衍生物，并通过¹ H 和¹³ C NMR 和质谱证实了它们的结构。根据生物测定数据，产物 3-(2-氯苯基) -N- {2-[2-(2,6-二氟苯甲酰基)肼羰基]-4-氟苯基}-5-甲基异恶唑-4-甲酰胺 ( 5f ) 的 LC ₅₀值) 对抗小菜蛾( P. xylostella ) 和小菜蛾( E. vitis )) 分别测定为 1.67 和 1.29 mg/L，高于多杀菌素、毒死蜱、β 氯氰菊酯和印苦楝素。