Bone implants with excellent antibacterial and osteogenic activity are beneficial in decreasing the risk of infection and accelerating the healing of injured bone tissue. Biodegradable Mg alloys are considered promising new platforms for treating bone-related diseases. However, the shortcomings of these alloys, including rapid corrosion and insufficient bio-functions (antibacteria and osteogenesis) severely limit their widespread applications. In the present work, ferric oxyhydroxide (FeOOH) nanosheets were grown in situ on plasma electrolytic oxidation (PEO)-coated Mg alloy through a simple and green immersion treatment. The highly-oriented FeOOH nanosheets completely sealed the porous structure of the PEO coating, and thereby significantly improved the corrosion resistance and biocompatibility of the Mg alloy. The prepared FeOOH films provided antibacterial activity through two modes. (i) the first is a photocatalytic effect, which prevents infections or contamination during storage and transportation and can be used to quickly sterilize the implants under sunlight before implantation into the human body. (ii) The second is a photothermal antibacterial effect, which has been shown to effectively kill Staphylococcus aureus that adhered to implants placed under the skin of mice using near infrared (NIR) light. Moreover, the enhanced corrosion resistance and synergistic biofunctions of the Mg and Fe ions of the FeOOH nanosheet-reinforced Mg alloy implants significantly facilitated cell adhesion, spreading, and proliferation and accelerated osteogenesis.

具有优异抗菌和成骨活性的骨植入物有利于降低感染风险和加速受伤骨组织的愈合。可生物降解的镁合金被认为是治疗骨相关疾病的新平台。然而，这些合金的缺点，包括快速腐蚀和生物功能不足（抗菌和成骨）严重限制了它们的广泛应用。在目前的工作中，羟基氧化铁（FeOOH）纳米片原位生长等离子电解氧化（PEO）涂层镁合金通过简单的绿色浸渍处理。高取向的FeOOH纳米片完全密封了PEO涂层的多孔结构，从而显着提高了镁合金的耐腐蚀性和生物相容性。制备的FeOOH薄膜通过两种模式提供抗菌活性。(i) 第一个是光催化作用，它可以防止储存和运输过程中的感染或污染，并可用于在植入人体之前在阳光下对植入物进行快速消毒。(ii) 第二种是光热抗菌作用，已被证明能有效杀死金黄色葡萄球菌使用近红外 (NIR) 光粘附在放置在小鼠皮肤下的植入物上。此外，FeOOH 纳米片增强镁合金植入物的 Mg 和 Fe 离子增强的耐腐蚀性和协同生物功能显着促进了细胞粘附、扩散和增殖，并加速了成骨。