Schisantherin A (Sch A) is a dibenzocyclooctadiene lignan monomer isolated from the fruit of Schisandra chinensis (Turcz.) Baill. (S. chinensis). At present, many studies have shown that Sch A has a wide range of pharmacological effects, including its anti-Parkinson and anti-inflammatory effects and ability to protect the liver, protect against ischemia-reperfusion (I/R) injury, suppress osteoclast formation, and improve learning and memory. Its mechanism may be related to the antioxidant, anti-inflammatory, and antiapoptotic properties of Sch A through the MAPK, NF-κB, AKT/GSK3β, and PI3K/AKT pathways. This is the first review of the recent studies on the pharmacological mechanism of Sch A.

中文翻译：

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五味子素A的药理作用研究进展

Schisantherin A (Sch A) 是一种从五味子(Turcz.) Baill的果实中分离出来的二苯并环辛二烯木脂素单体。( S. chinensis )。目前，许多研究表明，Sch A具有广泛的药理作用，包括其抗帕金森和抗炎作用以及保护肝脏、防止缺血再灌注（I/R）损伤、抑制破骨细胞形成的能力。 ，并提高学习和记忆力。其机制可能与 Sch A 通过 MAPK、NF- κ B、AKT/GSK3 β和 PI3K/AKT 通路的抗氧化、抗炎和抗凋亡特性有关。这是对近期关于Sch A的药理机制研究的第一次回顾。