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Clinical evaluation of switching from immediate-release to prolonged-release lithium in bipolar patients, poorly tolerant to lithium immediate-release treatment: A randomized clinical trial
Brain and Behavior ( IF 2.6 ) Pub Date : 2022-02-09 , DOI: 10.1002/brb3.2485
Federica Pelacchi 1 , Liliana Dell'Osso 2 , Emi Bondi 3 , Mario Amore 4 , Andrea Fagiolini 5 , Paolo Iazzetta 6 , Daniela Pierucci 1 , Manuela Gorini 1 , Elisa Quarchioni 1 , Alessandro Comandini 1 , Enrica Salvatori 1 , Agnese Cattaneo 1 , Maurizio Pompili 7 ,
Affiliation  

The effect of switching from lithium immediate release (Li-IR) to lithium prolonged release (Li-PR) on lithium-induced tremor after 1 and 12 weeks of treatment was evaluated in a randomized, multicenter, open trial, in bipolar patients from the participating sites with a tremor severity ≥2 (Udvalg for Kliniske Undersøgelser [UKU] rating scale) despite optimal lithium titration.

中文翻译:

对锂速释治疗耐受性差的双相患者从速释锂转换为缓释锂的临床评估:一项随机临床试验

在一项随机、多中心、开放试验中,一项随机、多中心、开放的试验评估了从锂速释 (Li-IR) 转换为锂缓释 (Li-PR) 对治疗 1 周和 12 周后锂诱发的震颤的影响。尽管优化锂滴定,震颤严重程度≥2(Udvalg for Kliniske Undersøgelser [UKU] 评定量表)的参与部位。
更新日期:2022-02-09
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