Synthesis ( IF 2.2 ) Pub Date : 2021-12-01 , DOI: 10.1055/a-1710-6289
David Whalley 1 , Michael Greaney 1
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The Smiles rearrangement has undergone a renaissance in recent years providing new avenues for non-canonical arylation techniques in both the radical and polar regimes. This short review will discuss recent applications of the reaction (from 2017 to late 2021), including its relevance to areas such as heterocycle synthesis and the functionalization of alkenes and alkynes as well as glimpses at new directions for the field.
1 Introduction
2 Polar Smiles Rearrangements
3 Radical Smiles: Alkene and Alkyne Functionalization
4 Radical Smiles: Rearrangements via C–X Bond Cleavage
5 Radical Smiles: Miscellaneous Rearrangements
6 Conclusions
中文翻译:
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微笑重排的最新进展:芳基化的新机遇
近年来,Smiles 重排经历了复兴,为激进和极地体制中的非规范芳基化技术提供了新途径。这篇简短的综述将讨论该反应的近期应用(从 2017 年到 2021 年末),包括它与杂环合成和烯烃和炔烃的官能化等领域的相关性,以及对该领域新方向的一瞥。
1 简介
2 Polar Smiles 重新排列
3 个激进的微笑:烯烃和炔烃功能化
4 个激进的微笑:通过 C–X 键裂解的重排
5个激进的微笑:杂项重新排列
6。结论