Metformin hydrochloride is widely used to treat diabetes mellitus. This review presents its physical and chemical properties and discusses methods of analysis that allow a quality assessment of metformin hydrochloride both as an individual drug and in combination with other antidiabetic medicines. The most widely used method is HPLC combined with spectrophotometry and other methods of analysis. The review is based on data from foreign and domestic articles and on our research results.

中文翻译：

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盐酸二甲双胍的理化性质及测定方法（综述）

盐酸二甲双胍被广泛用于治疗糖尿病。这篇综述介绍了它的物理和化学特性，并讨论了分析方法，这些分析方法可以对盐酸二甲双胍作为一种单独的药物和与其他抗糖尿病药物的组合进行质量评估。最广泛使用的方法是 HPLC 结合分光光度法和其他分析方法。该评论基于国内外文章的数据和我们的研究成果。