Lipase-Catalyzed Synthesis of Anthrone Functionalized Benzylic Amines via a Multicomponent Reaction in Supercritical Carbon Dioxide,ChemistrySelect

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Lipase-Catalyzed Synthesis of Anthrone Functionalized Benzylic Amines via a Multicomponent Reaction in Supercritical Carbon Dioxide
ChemistrySelect ( IF 1.9 ) Pub Date : 2022-02-02 , DOI: 10.1002/slct.202104517
Fengxi Li ₁ , Ciduo Wang ₁ , Yaning Xu ₁ , Xiaojun Gao ₂ , Yuelin Xu ₁ , Hanqing Xie ₁ , Peng Chen ₃ , Lei Wang ₁

Affiliation

Lipases have been used to catalyze the synthesis of anthrone-functionalized benzylic amines in supercritical carbon dioxide. Satisfactory yields and mild reaction conditions make this method highly viable for practical applications. Furthermore, this study provides a new example of a lipase-catalyzed organic reaction and is expected to expand the utilization of lipase in organic synthesis.