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Highlights of the Recent Patent Literature─Focus on Biocatalysis Innovation
Organic Process Research & Development ( IF 3.1 ) Pub Date : 2022-01-27 , DOI: 10.1021/acs.oprd.1c00417
David L. Hughes 1
Affiliation  

This review surveys recent advances in biocatalysis, with a primary focus on contributions from the patent literature since 2018, including reductive aminations, nitro reductions, amidations, carbon–carbon bond formation catalyzed by lipases and aldolases, and cascade biocatalysis. Examples of processes that have been designed and developed for the industrial preparation of pharmaceutical intermediates are highlighted.

中文翻译:

近期专利文献要闻─聚焦生物催化创新

本综述调查了生物催化的最新进展,主要关注自 2018 年以来专利文献的贡献,包括还原胺化、硝基还原、酰胺化、脂肪酶和醛缩酶催化的碳-碳键形成以及级联生物催化。重点介绍了为医药中间体的工业制备而设计和开发的工艺示例。
更新日期:2022-01-27
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