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Wound Dressing: From Nanomaterials to Diagnostic Dressings and Healing Evaluations
ACS Nano ( IF 15.8 ) Pub Date : 2022-01-20 , DOI: 10.1021/acsnano.1c08411
Qiankun Zeng 1, 2, 3, 4 , Xiaoliang Qi 5 , Guoyue Shi 1, 2, 3, 4 , Min Zhang 1, 2, 3, 4 , Hossam Haick 6, 7
Affiliation  

Wound dressings based on nanomaterials play a crucial role in wound treatment and are widely used in a whole range of medical settings, from minor to life-threatening tissue injuries. This article presents an educational review on the accumulating knowledge in this multidisciplinary area to lay out the challenges and opportunities that lie ahead and ignite the further and faster development of clinically valuable technologies. The review analyzes the functional advantages of nanomaterial-based gauzes and hydrogels as well as hybrid structures thereof. On this basis, the review presents state-of-the-art advances to transfer the (semi)blind approaches to the evaluation of a wound state to smart wound dressings that enable real-time monitoring and diagnostic functions that could help in wound evaluation during healing. This review explores the translation of nanomaterial-based wound dressings and related medical aspects into real-world use. The ongoing challenges and future opportunities associated with nanomaterial-based wound dressings and related clinical decisions are presented and reviewed.

中文翻译:

伤口敷料:从纳米材料到诊断敷料和愈合评估

基于纳米材料的伤口敷料在伤口治疗中发挥着至关重要的作用,并广泛用于从轻微到危及生命的组织损伤的各种医疗环境中。本文对这一多学科领域的知识积累进行了教育性回顾,以阐明摆在面前的挑战和机遇,并推动临床有价值技术的进一步和更快的发展。该综述分析了基于纳米材料的纱布和水凝胶及其混合结构的功能优势。在此基础上,该综述介绍了将评估伤口状态的(半)盲方法转移到智能伤口敷料的最新进展,从而实现实时监测和诊断功能,有助于伤口评估。康复。这篇综述探讨了基于纳米材料的伤口敷料和相关医学方面在现实世界中的应用。介绍并回顾了与基于纳米材料的伤口敷料和相关临床决策相关的持续挑战和未来机遇。
更新日期:2022-01-20
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