ABSTRACT

Streptomyces griseocarneus R132 is an actinobacterium capable of controlling fungi in sweet peppers. The crude S. griseocarneus R132 methanol extract was fractionated in a polystyrene-divinylbenzene column eluted with 20–100% acetone gradient. Compound 1 isolated from the 60% fraction was identified as 4-chlorocinnamic acid. This fraction and 4-chlorocinnamic acid inhibited Colletotrichum gloeosporioides growth by 28% and 65%, respectively, and reduced the diameter of lesions caused by the phytopathogen in Capsicum annuum L. fruits by 33.19% and 31.92%, respectively. The isolated 4-chlorocinnamic acid was not toxic to MRC-5 fibroblasts.

摘要

Streptomyces griseocarneus R132 是一种能够控制甜椒真菌的放线菌。粗制S. griseocarneus R132 甲醇提取物在聚苯乙烯-二乙烯基苯柱中分离，用​​ 20-100% 丙酮梯度洗脱。从 60% 馏分中分离出的化合物1被鉴定为 4-氯肉桂酸。该馏分和 4-氯肉桂酸分别抑制胶孢炭疽菌生长 28% 和 65%，并使辣椒果实中的植物病原体引起的病斑直径分别减少 33.19% 和 31.92%。分离的 4-氯肉桂酸对 MRC-5 成纤维细胞没有毒性。