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Direct Hydrodecarboxylation of Aliphatic Carboxylic Acids: Metal- and Light-Free
Organic Letters ( IF 4.9 ) Pub Date : 2022-01-07 , DOI: 10.1021/acs.orglett.1c04079
Euan B McLean 1 , David T Mooney 1 , David J Burns 2 , Ai-Lan Lee 1
Organic Letters ( IF 4.9 ) Pub Date : 2022-01-07 , DOI: 10.1021/acs.orglett.1c04079
Euan B McLean 1 , David T Mooney 1 , David J Burns 2 , Ai-Lan Lee 1
Affiliation
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A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.
中文翻译:
脂肪族羧酸的直接加氢脱羧:无金属和无光
已经开发了一种用于脂肪族羧酸直接加氢脱羧的温和且廉价的方法。该反应不需要金属、光或催化剂,使该协议操作简单、易于扩展且更具可持续性。至关重要的是,在大多数情况下不需要额外的 H 原子源,同时观察到广泛的底物范围和官能团耐受性。
更新日期:2022-01-21
中文翻译:

脂肪族羧酸的直接加氢脱羧:无金属和无光
已经开发了一种用于脂肪族羧酸直接加氢脱羧的温和且廉价的方法。该反应不需要金属、光或催化剂,使该协议操作简单、易于扩展且更具可持续性。至关重要的是,在大多数情况下不需要额外的 H 原子源,同时观察到广泛的底物范围和官能团耐受性。