Pakistan, being an agro-based economy, is considered most vulnerable to the impacts of climate change. The country is susceptible to many natural catastrophes and climate-induced events due to intra-geographical and intra-topographical disparities. This paper is an attempt to measure the relative vulnerability of diverse topographies in rural areas of Pakistan using vulnerability and capacity index tool. The results are based on the findings of primary survey data (350 households from 17 rural communities). Accordingly, and as expected, the key relative differences are attributed to topographical conditions besides the basic quandary of rural areas of Pakistan. The topographical attributes are largely linked to the nature of hazards and relative impacts. While the other aspects of vulnerability in all topographies stem out of inappropriate infrastructure, low education, and institutional factors. The absence of multi-sectoral and productive economic opportunities also poses an adverse impact on the resilience of households in rural areas. The women and households headed by females are found relatively more vulnerable than male-headed households.