In this work, a tetraphenylmethane porous organic framework (TPOF) membrane was prepared by mixing fluorescent TPOF into poly (vinylidene fluoride) (PVDF). Combining the advantages of membrane and TPOF, the TPOF membrane exhibited a continuous porous structure, good flexibility, hydrophobic properties and excellent fluorescence performance. Owing to the remarkable selectivity towards quinoxalines, the TPOF membrane was used as a fluorescence sensor for rapid quinoxalines analysis. The mechanism of the TPOF selectivity was studied by density functional theory (DFT) calculation experiments. Compared to other growth promoting drugs, the lowest unoccupied molecular orbital (LUMO) energy state difference between TPOF and quinoxalines was the largest. The linear ranges for the determination of carbadox and olaquindox were 0.3–20.0 and 0.6–20.0 μmol/L with the correlation coefficients (R²) of 0.9904 and 0.9943, respectively. The limit of detection (LOD, S/N = 3) were 96 and 182 nmol/L, respectively. Furthermore, this fluorescence sensor was used for olaquindox determination in feed samples, and the recoveries were varied from 97.4% to 107.7%. The results obtained by the proposed fluorescence method showed a good agreement with that obtained from HPLC method. Overall, this fluorescence sensor has been confirmed excellent performance in the quinoxalines analysis, which reveals extensive application in rapid residual quinoxalines analysis in feed samples.

在这项工作中，通过将荧光TPOF混合到聚偏二氟乙烯 (PVDF) 中制备了四苯基甲烷多孔有机骨架 ( TPOF ) 膜。结合了膜和TPOF的优点，TPOF膜表现出连续的多孔结构、良好的柔韧性、疏水性和优异的荧光性能。由于对喹喔啉的显着选择性，TPOF膜被用作快速分析喹喔啉的荧光传感器。TPOF的机制通过密度泛函理论 (DFT) 计算实验研究了选择性。与其他促生长药物相比，TPOF和喹喔啉的最低未占分子轨道 (LUMO) 能态差异最大。卡巴氧和喹乙醇的测定线性范围分别为 0.3-20.0 和 0.6-20.0 μmol/L，相关系数 (R ² ) 分别为 0.9904 和 0.9943。检测限（LOD，S/N  = 3）分别为 96 和 182 nmol/L， 分别。此外，该荧光传感器用于测定饲料样品中的喹乙醇，回收率从 97.4% 到 107.7% 不等。所提出的荧光方法获得的结果与 HPLC 方法获得的结果非常吻合。总体而言，该荧光传感器在喹喔啉分析中已被证实具有出色的性能，这揭示了其在饲料样品中快速残留喹喔啉分析中的广泛应用。