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Nucleophilic reactions of ethyl (Z)-2‑bromo-4,4,4-trifluorobut-2-enoate: One molecule – various heterocycles
Journal of Fluorine Chemistry ( IF 1.7 ) Pub Date : 2021-12-26 , DOI: 10.1016/j.jfluchem.2021.109946 Ilya A. Tyumentsev 1 , Valentina A. Kobelevskaya 1 , Igor A. Ushakov 1 , Alexander Yu. Rulev 1
中文翻译：
(Z)-2-bromo-4,4,4-trifluorobut-2-enoate 的亲核反应：一个分子 - 各种杂环
更新日期：2021-12-31
Journal of Fluorine Chemistry ( IF 1.7 ) Pub Date : 2021-12-26 , DOI: 10.1016/j.jfluchem.2021.109946 Ilya A. Tyumentsev 1 , Valentina A. Kobelevskaya 1 , Igor A. Ushakov 1 , Alexander Yu. Rulev 1
Affiliation
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The synthetic approach to different fluorinated heterocycles based on ethyl (Z)-2‑bromo-4,4,4-trifluorobut-2-enoate and binucleophiles is described. The assembly of all heterocyclic structures proceeds through the formation of the product of conjugate nucleophilic addition as a key step.
中文翻译：
(Z)-2-bromo-4,4,4-trifluorobut-2-enoate 的亲核反应：一个分子 - 各种杂环
描述了基于乙基 ( Z )-2-bromo-4,4,4-trifluorobut-2-enoate 和双亲核试剂的不同氟化杂环的合成方法。所有杂环结构的组装都是通过形成共轭亲核加成产物作为关键步骤进行的。
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