Highly Regioselective Copper-Catalyzed Transfer Hydrodeuteration of Unactivated Terminal Alkenes,Chemistry - A European Journal

当前位置： X-MOL 学术 › Chem. Eur. J. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Highly Regioselective Copper-Catalyzed Transfer Hydrodeuteration of Unactivated Terminal Alkenes
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2021-12-09 , DOI: 10.1002/chem.202104340
Albert Reyes ₁ , Emanuel Rivera Torres ₁ , Zoua Pa Vang ₁ , Joseph R Clark ₁

Affiliation

Precision deuteration of unactivated alkenes: A copper-catalyzed alkene transfer hydrodeuteration for the synthesis of precisely deuterated small molecules is described. It is the most regio- and chemoselective transfer hydrodeuteration of unactivated terminal alkenes reported to date. The transformation was performed across a broad scope of substrates and even demonstrated on two natural product derivatives.