In this study, six new acylthiourea, bearing naphthoquinone moiety, sensors were synthesized in high yield (88–96%) and characterized using ¹H/¹³C NMR, FT-IR and HRMS techniques. All synthesized sensors (4a-f) showed shifts in absorbance and colorimetric changes by CN⁻, F⁻, AcO⁻, and H₂PO₄⁻. However, 4e showed a chromogenic different sensitivity response to CN⁻ and F⁻ against competing anions such as AcO⁻ and H₂PO₄⁻ in DMSO. Furthermore, CN⁻ added 4e showed an increase at the emission intensity and intensive fluorimetric color change was observed in UV-light (λex. 365 nm). All sensors showed chromogenic selectivity towards CN⁻ in aqueous solutions (in DMSO/H₂O: 1:1, v/v). Interaction mechanisms between 4e and CN⁻ and F⁻ anions were investigated by experimental studies using various spectroscopic methods such as UV/Vis, fluorescence, ¹H/¹⁹F NMR, and DFT calculation. The results showed that CN⁻ interacts with 4e by the main mechanism as nucleophilic addition of cyanide to 3,5-dinitrophenyl moiety while F⁻ caused an occurrence of imidazole ring-closing due to deprotonation of NH₂. LOD values are reported as 2.7 μM for sensor 4e. Moreover, interaction studies were carried out on food sample such as bitter almond, sprouting potato and apricot seed. Furthermore, UV/vis responses were obtained between sensors (4a-f) and the cations, and found selectivity towards Hg²⁺ in DMSO.

在本研究中，以高产率 (88–96%) 合成了六种带有萘醌部分的新型酰基硫脲传感器，并使用¹ H/ ¹³ C NMR、FT-IR 和 HRMS 技术进行了表征。所有合成的传感器 ( 4a-f ) 都显示出由 CN ^-、F ^-、AcO ^-和 H ₂ PO ₄ ^-引起的吸光度和比色变化的变化。然而，4e在 DMSO 中对 CN ^-和 F ^-对竞争性阴离子（例如 AcO ^-和 H ₂ PO ₄ ^{- ）}显示出不同的显色灵敏度响应。此外，CN^-添加的4e显示发射强度增加，并且在紫外光（λex. 365 nm）中观察到强烈的荧光颜色变化。所有传感器都显示出对水溶液中CN ^{- 的}显色选择性（在 DMSO/H ₂ O 中：1:1，v/v）。4e与CN ^-和F ^-阴离子之间的相互作用机制通过使用各种光谱方法如UV/Vis、荧光、¹ H/ ¹⁹ F NMR和DFT计算的实验研究来研究。结果表明，CN ^-与4e相互作用的主要机制是氰化物与 3,5-二硝基苯基部分的亲核加成，而 F^-由于NH _{2 的}去质子化导致咪唑闭环的发生。传感器4e 的LOD 值报告为 2.7 μM 。此外，还对苦杏仁、发芽马铃薯和杏子等食品样品进行了相互作用研究。此外，在传感器 ( 4a-f ) 和阳离子之间获得了 UV/vis 响应，并发现对DMSO 中的Hg ²⁺具有选择性。