Bio-Design and Manufacturing ( IF 8.1 ) Pub Date : 2021-12-02 , DOI: 10.1007/s42242-021-00165-0 Silvia Santoni 1, 2 , Simone G. Gugliandolo 1, 2 , Bianca M. Colosimo 1 , Mattia Sponchioni 2 , Davide Moscatelli 2
|
The multidisciplinary research field of bioprinting combines additive manufacturing, biology and material sciences to create bioconstructs with three-dimensional architectures mimicking natural living tissues. The high interest in the possibility of reproducing biological tissues and organs is further boosted by the ever-increasing need for personalized medicine, thus allowing bioprinting to establish itself in the field of biomedical research, and attracting extensive research efforts from companies, universities, and research institutes alike. In this context, this paper proposes a scientometric analysis and critical review of the current literature and the industrial landscape of bioprinting to provide a clear overview of its fast-changing and complex position. The scientific literature and patenting results for 2000–2020 are reviewed and critically analyzed by retrieving 9314 scientific papers and 309 international patents in order to draw a picture of the scientific and industrial landscape in terms of top research countries, institutions, journals, authors and topics, and identifying the technology hubs worldwide. This review paper thus offers a guide to researchers interested in this field or to those who simply want to understand the emerging trends in additive manufacturing and 3D bioprinting.
Graphic abstract
中文翻译：
3D 生物打印：现状和趋势——文献和工业实践指南
生物打印的多学科研究领域结合了增材制造、生物学和材料科学，以创建具有模仿自然活组织的三维结构的生物结构。对个性化医疗的需求不断增加，进一步提高了对复制生物组织和器官的可能性的高度兴趣，从而使生物打印在生物医学研究领域站稳脚跟，并吸引了公司、大学和研究机构的广泛研究。机构一样。在此背景下，本文提出了对当前文献和生物打印产业格局的科学计量分析和批判性回顾，以清晰概述其快速变化和复杂的地位。通过检索 9314 篇科学论文和 309 项国际专利，对 2000-2020 年的科学文献和专利申请结果进行审查和批判性分析，以从顶级研究国家、机构、期刊、作者和主题的角度描绘科学和工业格局，并确定全球的技术中心。因此，这篇综述为对该领域感兴趣的研究人员或那些只想了解增材制造和 3D 生物打印新兴趋势的研究人员提供了指南。
京公网安备 11010802027423号