Label-Free Electrochemiluminescence Imaging of Single-Cell Adhesions by Using Bipolar Nanoelectrode Array,Chemistry - A European Journal

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Label-Free Electrochemiluminescence Imaging of Single-Cell Adhesions by Using Bipolar Nanoelectrode Array
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2021-11-30 , DOI: 10.1002/chem.202103964
Xiang Qin ₁ , Hua-Jiang Jin ₁ , Xiuxiu Li ₂ , Jian Li ₁ , Jian-Bin Pan ₁ , Kang Wang ₁ , Songqin Liu ₂ , Jing-Juan Xu ₁ , Xing-Hua Xia ₁

Affiliation

A label-free method for fast and positive electrochemiluminescence (ECL) imaging of single cells by bipolar nanoelectrode array is proposed using oxygen as the electrochemical probe. The successful imaging is achieved by transient generation of difference in oxygen concentration over the nanoelectrodes covered with or without cells. Thus, cell morphology and adhesion strength can be imaged.

中文翻译：

使用双极纳米电极阵列对单细胞粘附进行无标记电化学发光成像

提出了一种使用氧气作为电化学探针的双极纳米电极阵列对单个细胞进行快速正向电化学发光 (ECL) 成像的无标记方法。成功的成像是通过在覆盖有或没有细胞的纳米电极上瞬时产生氧浓度差异来实现的。因此，可以对细胞形态和粘附强度进行成像。

更新日期：2022-01-13

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