We have synthesised the robust molybdenum oxide supported on zirconium oxide (MoO₃/ZrO₂) by a simple wet-impregnation method. It proved an effective catalyst for synthesising eleven novel dihydropyridine derivatives in excellent yields (92–96%). The one-pot four-component fusion involved dimethyl-2-amine pyridine, diethyl but-2-ynedioate, various benzaldehydes and malononitrile in ethanol. The swift reactions at room temperature were accomplished in <18 min. The nanocomposite catalyst is stable up to five successive runs with similar catalytic activity. Swift reaction, recyclability, excellent yields, mild conditions, simple workup and column-free protocol are the advantages of this method.

我们已经通过简单的湿浸渍法合成了负载在氧化锆上的坚固的氧化钼 (MoO ₃ /ZrO ₂ )。它被证明是一种有效的催化剂，可以以优异的产率 (92-96%) 合成 11 种新型二氢吡啶衍生物。一锅四组分融合包括二甲基-2-胺吡啶、丁-2-炔二酸二乙酯、各种苯甲醛和丙二腈的乙醇溶液。室温下的快速反应在 <18 分钟内完成。纳米复合催化剂在具有相似催化活性的连续五次运行中都是稳定的。该方法的优点是反应迅速、可回收、收率高、条件温和、后处理简单和无柱协议。