A palladium-catalyzed cascade approach for the synthesis of 3,3a,4,6,7,8,9,9a-octahydro-1H-benzo[f]isoindole-1,5(2H)-diones,Journal of Chemical Research

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A palladium-catalyzed cascade approach for the synthesis of 3,3a,4,6,7,8,9,9a-octahydro-1H-benzo[f]isoindole-1,5(2H)-diones
Journal of Chemical Research ( IF 1.0 ) Pub Date : 2021-11-30 , DOI: 10.1177/17475198211058653
Dong Cheng ₁ , Xiangzhen Meng ₁ , Dan Wang ₁ , Xuan Zhao ₁ , Yusheng Wang ₁ , Zhiyu Ji ₁

Affiliation

A synthetic method for the preparation of 3,3a,4,6,7,8,9,9a-octahydro-1H-benzo[f]isoindole-1,5(2H)-diones from 1,6-dienes and vinyl iodides is developed using PdCl₂(PPh₃)₂ as the catalyst. The presented approach exhibits a good functional group tolerance and affords moderate yields of the products. A mechanism is also proposed.

中文翻译：

钯催化级联方法合成 3,3a,4,6,7,8,9,9a-octahydro-1H-benzo[f]isoindole-1,5(2H)-diones

一种由 1,6-二烯和3,3a,4,6,7,8,9,9a-octahydro- 1H -benzo [ f ] isoindole -1,5( 2H )-diones制备的合成方法使用 PdCl ₂ (PPh ₃ ) ₂作为催化剂开发乙烯基碘化物。所提出的方法表现出良好的官能团耐受性，并提供中等产率的产品。还提出了一种机制。

更新日期：2021-11-30

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