Hydrogel has a similar structure and function as the extracellular matrix and is expected to be used for wound adhesion and hemostasis. However, traditional hydrogels have poor adhesion and no self-healing function, and mechanical properties are also limited. Inspired by mussel and adherent DNA, the triple-cross-linking conductive self-healing hydrogel (CaSA-GAD hydrogel) containing calcium ions (Ca²⁺), sodium alginate, acrylated guanine, acrylamide, and acrylated dopamine was constructed through UV irradiation, including a G–C pairing hydrogen bond dynamic network, a chemical cross-linking network, and an ionic cross-linking dynamic network. The hydrogel exhibits strong adhesion to various surfaces and peeling properties in the bonding of tissues. With high toughness, the hydrogel can be stretched and compressed without damage. The self-healing property further ensures the mechanical properties of the hydrogel. By loading calcium ions to reduce the impedance of the hydrogel greatly, the wound can be monitored at the same time when the wound is bonded. Both fresh and freeze-dried hydrogel can be used to bond the wound on pork stomach and the scope of application of as wound adhesive increases. In addition, the hydrogel can be used as a sensitive sensor to monitor human movement.

中文翻译：

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受贻贝和 DNA 启发的具有三重交联的高粘性、导电和自愈水凝胶，用于伤口粘附和人体运动传感

水凝胶具有与细胞外基质相似的结构和功能，有望用于伤口粘连和止血。然而，传统的水凝胶附着力差，没有自愈功能，力学性能也有限。受贻贝和粘附 DNA 的启发，三重交联导电自修复水凝胶（CaSA-GAD 水凝胶）含有钙离子（Ca ²⁺)、海藻酸钠、丙烯酸化鸟嘌呤、丙烯酰胺和丙烯酸化多巴胺是通过紫外线照射构建的，包括 G-C 配对氢键动态网络、化学交联网络和离子交联动态网络。水凝胶对各种表面具有很强的粘附性，并在组织粘合中具有剥离特性。具有高韧性，水凝胶可以被拉伸和压缩而不会损坏。自修复性能进一步保证了水凝胶的机械性能。通过加载钙离子大大降低水凝胶的阻抗，可以在伤口粘合的同时监测伤口。新鲜水凝胶和冻干水凝胶均可用于猪肚创面的粘合，随着创面粘合剂的应用范围不断扩大。此外，