FDG PET/CT在结直肠癌辅助化疗后随访患者中的应用,Egyptian Journal of Radiology and Nuclear Medicine

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FDG PET/CT在结直肠癌辅助化疗后随访患者中的应用
Egyptian Journal of Radiology and Nuclear Medicine ( IF 0.7 ) Pub Date : 2021-11-29 , DOI: 10.1186/s43055-021-00655-2
Remon Zaher Elia ₁ , Rafik Abdelazem Elbastawessy ₁ , Hanaa Abdelkader Abdelmgeguid ₁ , Ahmed Mohamed Bassiouny ₁

Affiliation

18F-2-氟-2-脱氧-d-葡萄糖 (18F-FDG) 正电子发射断层扫描计算机断层扫描 (PET-CT) 是一种评估和测量癌细胞代谢亲和力的成像方法，作为潜在细胞活动和活力等提供解剖和代谢信息。18F-FDG PET-CT有利于检测结直肠癌患者化疗和放疗后的局部复发、远处转移和监测肿瘤活力。严格遵守既定方案、技术流程和良好的患者准备对于产生最佳结果至关重要。该试验的目的是了解 PET/CT 在随访已切除结直肠癌并完成辅助化疗回合的患者中的作用。在这项研究中，PET/CT 早期检测到肝脏沉积物、肺肿块、骨沉积和相当大的 LN。PET/CT 提供了有用的信息，对疾病管理产生了相当大的影响，能够尽早发现复发性疾病，并以高精度评估治疗反应。它在手术床疤痕、代谢活跃的小淋巴结、肝脏局灶性病变、腹膜沉积物、肺继发性和骨沉积物中检测到存活的残留肿瘤细胞，避免了不必要的手术。由于其检测精度高和识别复发性疾病的能力，FDG-PET-CT 成像可有效评估治疗后疑似肿瘤复发或远处转移的结直肠癌患者。能够以高精度评估治疗反应，尽早发现复发性疾病。它在手术床疤痕、代谢活跃的小淋巴结、肝脏局灶性病变、腹膜沉积物、肺继发性和骨沉积物中检测到存活的残留肿瘤细胞，避免了不必要的手术。由于其检测精度高和识别复发性疾病的能力，FDG-PET-CT 成像可有效评估治疗后疑似肿瘤复发或远处转移的结直肠癌患者。能够以高精度评估治疗反应，尽早发现复发性疾病。它在手术床疤痕、代谢活跃的小淋巴结、肝脏局灶性病变、腹膜沉积物、肺继发性和骨沉积物中检测到存活的残留肿瘤细胞，避免了不必要的手术。由于其检测精度高和识别复发性疾病的能力，FDG-PET-CT 成像可有效评估治疗后疑似肿瘤复发或远处转移的结直肠癌患者。

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FDG PET/CT in follow UP patients with colorectal carcinoma after adjuvant chemotherapy

18F-2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) is a method of imaging that assesses and measures metabolic avidity in cancer cells, acting as a proxy for underlying cellular activity and vitality and so providing anatomic and metabolic information. 18F-FDG PET-CT is beneficial for detecting local recurrence, distant metastases, and monitoring tumor viability after chemotherapy and radiotherapy in patients with colorectal cancer. Strict adherence to set protocols, technological processes, and good patient preparation are essential to produce the greatest results. The goal of the trial was to see how useful PET/CT was in following up on patients who had resected colorectal cancer and had completed adjuvant chemotherapy rounds. In this study, PET/CT early detected hepatic deposits, pulmonary masses, bone deposits, and sizable LNs. PET/CT provided useful information and had a considerable impact on disease management, enabling the detection of recurrent disease as early as possible with high accuracy in assessment of therapeutic response. It detected viable residual tumor cells in operative bed scar, small metabolically active LNs, hepatic focal lesions, peritoneal deposits, pulmonary secondaries, and bone deposits avoiding unnecessary surgeries. Because of its high accuracy in detection and capacity to identify recurrent illness, FDG-PET-CT imaging is effective in evaluating post-therapeutic colorectal cancer patients with suspected tumor recurrence or distant metastases.

更新日期：2021-11-30

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