当前位置：
X-MOL 学术
›
J. Org. Chem.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Synthesis of 5H-Chromeno[2,3-d]pyrimidin-5-one Derivatives via Microwave-Promoted Multicomponent Reaction
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2021-11-23 , DOI: 10.1021/acs.joc.1c02434 Biwei Zhang 1 , Hongjian Yang 2 , Taimin Wang 1 , Xuanzhen Han 1 , Haiyan Sun 1 , Lijing Fang 3 , Hongbin Zhai 2 , Bin Cheng 1
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2021-11-23 , DOI: 10.1021/acs.joc.1c02434 Biwei Zhang 1 , Hongjian Yang 2 , Taimin Wang 1 , Xuanzhen Han 1 , Haiyan Sun 1 , Lijing Fang 3 , Hongbin Zhai 2 , Bin Cheng 1
Affiliation
|
A microwave-promoted multicomponent reaction of 3-formylchromones, amines, and paraformaldehyde was achieved under catalyst-free and solvent-free conditions, delivering 5H-chromeno[2,3-d]pyrimidin-5-one derivatives in good to excellent yields via an unexpected annulation pathway, which further expanded the synthetic application of paraformaldehyde as a C1 building block.
中文翻译：
微波促进多组分反应合成5H-Chromeno[2,3-d]pyrimidin-5-one衍生物
在无催化剂和无溶剂条件下实现了 3-甲酰基色酮、胺和多聚甲醛的微波促进多组分反应，以良好至优异的产率提供 5 H-色烯[2,3 - d ]嘧啶-5-酮衍生物通过一个意想不到的环化途径，进一步扩大了多聚甲醛作为 C1 结构单元的合成应用。
更新日期：2021-12-17
中文翻译：
微波促进多组分反应合成5H-Chromeno[2,3-d]pyrimidin-5-one衍生物
在无催化剂和无溶剂条件下实现了 3-甲酰基色酮、胺和多聚甲醛的微波促进多组分反应，以良好至优异的产率提供 5 H-色烯[2,3 - d ]嘧啶-5-酮衍生物通过一个意想不到的环化途径，进一步扩大了多聚甲醛作为 C1 结构单元的合成应用。
京公网安备 11010802027423号