Impact of cyclofructan derivatives as efficient chiral selector in chiral analysis: An overview,Chirality

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Impact of cyclofructan derivatives as efficient chiral selector in chiral analysis: An overview
Chirality ( IF 2.8 ) Pub Date : 2021-11-21 , DOI: 10.1002/chir.23396
Hassan Y Aboul-Enein ₁ , Valliappan Kannappan ₂ , Selvakumar Kanthiah ₃

Affiliation

The development of chiral selectors for the separation and analysis of chiral molecules has been an evolving process happening over three decades, since the introduction of the first chiral stationary phase (CSP) in 1938. The main impetus for designing new chiral selectors is to get to most promising one which has a broad chiral recognition property, separation capability for a wide range of chiral analytes, and the cost-effective CSP, which is also a major concern. Today, we have more than 100 commercially available CSPs, and these are prepared by coating or immobilizing the classical chiral selectors on to the chromatographic support, normally, silica gel. The purpose of this review is to look at progress and the impact of cyclofructan derivatives, a novel chiral selector introduced recently, for performing chiral analysis.

中文翻译：

环果聚糖衍生物作为手性分析中有效手性选择剂的影响：概述

自 1938 年引入第一个手性固定相 (CSP) 以来，用于手性分子分离和分析的手性选择器的开发一直是一个不断发展的过程。设计新的手性选择器的主要动力是获得最有希望的一种，它具有广泛的手性识别特性、对多种手性分析物的分离能力以及成本效益高的 CSP，这也是一个主要问题。今天，我们有 100 多种市售 CSP，这些 CSP 是通过将经典手性选择剂涂覆或固定在色谱载体（通常是硅胶）上制备的。本综述的目的是研究环果聚糖衍生物（一种最近推出的新型手性选择剂）用于进行手性分析的进展和影响。

更新日期：2021-11-21

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