α-(Trifluoromethyl)styrene and its derivatives have found wide applications in the fields of pharmaceuticals, agrochemicals, and advanced materials. They are also versatile trifluoromethyl-containing building blocks for the preparation of various trifluoromethyl-containing, fluorine-containing or nonfluorinated compounds. Recently, great efforts have been made to develop diverse reactions for rapidly accessing a wide range of valuable gem‑difluoroalkenes and gem‑difluoroalkylated compounds via defluorinative reaction or the defluorinative ipso-functionalization reaction of α-(trifluoromethyl)styrenes, respectively. In contrast, α-(trifluoromethyl)styrenes remain notably underdeveloped with respect to their use in cycloaddition and hydroaddition reaction with retaining of three CF bonds. This short review herein is aimed to summarize the recent progress on the cycloaddition and hydroaddition reaction including nucleophilic, radical and transition metal-catalyzed addition of α-(trifluoromethyl)styrenes without accompanying defluorination.

α-(三氟甲基)苯乙烯及其衍生物在医药、农用化学品和先进材料等领域有着广泛的应用。它们还是用于制备各种含三氟甲基、含氟或非氟化化合物的通用含三氟甲基结构单元。最近，人们努力开发多种反应，通过脱氟反应或脱氟ipso快速获得各种有价值的宝石-二氟烯烃和宝石-二氟烷基化化合物。-α-(三氟甲基)苯乙烯的官能化反应，分别。相比之下，α-(三氟甲基)苯乙烯在环加成和加氢加成反应中的应用仍显着落后，并保留了三个 C F 键。本文的简短综述旨在总结环加成和加氢加成反应的最新进展，包括亲核、自由基和过渡金属催化的 α-（三氟甲基）苯乙烯加成，而没有伴随的脱氟。