Statement of problem

Immediate implant placement provides a popular therapeutic option. However, compromised sockets may jeopardize the treatment outcome.

Purpose

The purpose of this systematic review and meta-analysis was to investigate the treatment outcome in terms of the implant survival rate and success parameters of immediate implant placement in compromised extraction sockets.

Material and methods

An electronic search was conducted in PubMed, Embase, Cochrane Library, and ISI Web of Science up to January 2021. Studies evaluating implant survival rate and main success parameters were included for a qualitative and quantitative analysis (risk ratio and mean difference).

Results

In total, 43 studies with analysis of 4825 sockets were included. Compared with the noncompromised sockets, the compromised group showed no significant differences in implant survival rates (risk ratio=0.992; 95% confidence interval (CI)=0.979 to 1.005; P=.246). No significant statistical differences were found in marginal bone level at ≤12 months (mean difference [MD]=0.033; 95% CI=-0.012 to 0.078; P=.154) or esthetic parameters.

Conclusions

Immediate implant placement in compromised sites does not appear to decrease the survival and success rates. However, randomized clinical trials with large sample sizes should be conducted to draw a definite conclusion about the efficacy and safety of this treatment protocol in compromised sockets.

中文翻译：

---

在受损牙槽窝中立即植入种植体：系统评价和荟萃分析

问题陈述

即刻种植体植入提供了一种流行的治疗选择。然而，受损的插座可能会危及治疗结果。

目的

本系统评价和荟萃分析的目的是调查受损拔牙槽中即刻种植体植入的种植体存活率和成功参数方面的治疗结果。

材料与方法

截至 2021 年 1 月，在 PubMed、Embase、Cochrane 图书馆和 ISI Web of Science 中进行了电子检索。评估种植体存活率和主要成功参数的研究纳入定性和定量分析（风险比和平均差）。

结果

总共纳入了 43 项研究，分析了 4825 个插槽。与未受损的牙槽窝相比，受损组的种植体存活率没有显着差异（风险比=0.992；95%置信区间（CI）=0.979至1.005；P =.246 ）。≤12个月时边缘骨水平（​​平均差[MD]=0.033；95% CI=-0.012至0.078；P =.154）或美学参数未发现显着统计学差异。

结论

在受损部位立即植入种植体似乎不会降低存活率和成功率。然而，应进行大样本量的随机临床试验，以得出关于该治疗方案在受损插座中的有效性和安全性的明确结论。